Sonothrombolysis with Magnetically Targeted Microbubbles
نویسندگان
چکیده
منابع مشابه
Sonothrombolysis with BR38 Microbubbles Improves Microvascular Patency in a Rat Model of Stroke
BACKGROUND Early recanalization of large cerebral vessels in ischemic stroke is associated with improved clinical outcome, however persisting hypoperfusion leads to poor clinical recovery despite large vessel recanalization. Limited experimental sonothrombolysis studies have shown that addition of microbubbles during treatment can improve microvascular patency. We aimed to determine the effect ...
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OBJECTIVE This study aimed to develop targeted cationic microbubbles conjugated with a CD105 antibody (CMB105) for use in targeted vascular endothelial cell gene therapy and ultrasound imaging. We compared the results with untargeted cationic microbubbles (CMB) and neutral microbubbles (NMB). METHODS CMB105 were prepared and compared with untargeted CMB and NMB. First, the microbubbles were c...
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ژورنال
عنوان ژورنال: Ultrasound in Medicine & Biology
سال: 2019
ISSN: 0301-5629
DOI: 10.1016/j.ultrasmedbio.2018.12.014